a Record control number 000304202600009

a ISSN 1558-7673

a Original cataloging agency NEU GrandLibrary

a Language code of text/sound track or separate title eng

a Classification number QZ200

b Item number .P74 2012

a Personal name Akdogan, Bulent.

h Medium Electronic Document

a Title Prevalence and Predictors of Benign Lesions in Renal Masses Smaller Than 7 cm Presumed to be Renal Cell Carcinoma.

c Statement of responsibility, etc Bulent Akdogan, Ahmet Gudeloglu, Kubilay Inci, Levent Mert Gunay, Artan Koni, Haluk Ozen.

c Date of publication, distribution, etc 2012.

b Name of publisher, distributor, etc Cig Media Group,

a Place of publication, distribution, etc Dallas :

a Summary, etc The present study was designed to determine the incidence and predictive factors of benign renal lesions in 450 patients who underwent surgical removal of solitary renal masses <7 cm in diameter. Of the 450 renal masses, 88 (19.9%) were benign lesions. Female sex, nephron-sparing surgery, surgery between 1990 and 1996, cystic components on imaging, and small tumors (<4 cm) were independently associated with benign pathology. Purpose: To determine the association between preoperative parameters with final benign pathology in patients who underwent surgical removal of solitary renal masses <7 cm in diameter. Materials and Methods: A database of 450 patients without metastatic disease who underwent radical nephrectomy or nephron-sparing surgery (NSS) for removal of renal masses <7 cm between January 1990 and December 2009 was reviewed. Age, sex, symptoms, year and type of surgery, solid or cystic appearance, and tumor size were analyzed as presumed predictors of benign pathology. Multivariate analysis was performed to identify parameters associated with benign pathology. Results: In all, 88 (19.9%) of the tumors were benign, including 39 (8.7%) oncocytomas and 22 (4.9%) angiomyolipomas. The benign lesion rate for tumors <= 2, 2.1-4, and 4.1-7 cm was 30.3%, 27.1%, and 12.5%, respectively (2P < .001). For the periods of 1990-1996, 1997-2003, and 2004-2009, the frequency of benign tumors was 25%, 17.3%, and 18.4% (2P = .271), the incidental tumor rate was 48.1%, 60.4%, and 63.8% (2P = .027), mean tumor size was 5, 4.6, and 4.1 cm (2P < .001), and the NSS rate was 28.8%, 43.2%, and 52.7% (2P < .001), respectively. Logistic regression analysis revealed that female sex, NSS, surgery between 1990 and 1996, cystic components on imaging, and small tumors (<4 cm) based on radiologic examination were independently associated with benign pathology (odds ratio [OR] = 3.26, 2.56, 2.43, 2.41, and 1.96, respectively). Conclusions: The incidence of incidental and small tumors amenable to NSS increased over time. Female sex was the strongest predictor of benign pathology. Clinical Genitourinary Cancer, Vol. 10, No. 2, 121-5 (c) 2012 Elsevier Inc. All rights reserved.

a Topical term or geographic name as entry element Oncology

a Topical term or geographic name as entry element Near East University Article

a Topical term or geographic name as entry element Yakın Doğu Üniversitesi Makale

a Topical term or geographic name as entry element Urology & Nephrology

a Topical term or geographic name as entry element Benign pathology

a Topical term or geographic name as entry element Histology

a Topical term or geographic name as entry element Nephrectomy

g Relationship information JUN 2012, Vol 10 Issue 2, p121-125

x International Standard Serial Number 15587673

t Title Clinical Genitourinary Cancer

u Uniform Resource Identifier http://library.neu.edu.tr:2048/login?url=http://dx.doi.org/10.1016/j.clgc.2012.01.005